(in order of appearance)
| Deianeira: | Heracles’ current wife |
| Nurse: | servant and confidant of Deianeira |
| Hyllus: | son of Deianeira and Heracles |
| Chorus of Women of Trachis: | women of the city |
| Messenger: | an older citizen |
| Lichas: | herald of Heracles |
| Iole and Captives: | women that Heracles sends home as war prizes |
| Old Man: | leader of the soldiers with the hero |
| Heracles: | a servant of Jason’s household |
| Soldiers and Attendants: | greatest of Greek heroes, son of Zeus and Alcmene |